Fitting a key into a lock may seem like a simple task, but researchers are using a method that involves testing thousands of keys to unlock the functions of enzymes, and their findings could open the ...

Researchers have identified how a single mutation in the GPX4 enzyme causes neurons to undergo ferroptosis, leading to severe early-onset dementia.

Researchers at Helmholtz Munich, the Technical University of Munich and the LMU University Hospital Munich uncovered a ...

The protein community is awash in data. As of October, the UniProt database of protein sequences had more than 44 million entries. UniProt serves as a clearinghouse for sequences. Researchers who ...

While there are several bacteria and viruses causing pneumonia, the research team looked specifically at Streptococcus pneumoniae.

Synthetic biology is a growing field of research that is aiming to create a new kind of organism. Engineering synthetic proteins that can perform simple cellular functions as they would in real life ...

It has been known in biology for a long time that the excited oxygen molecule singlet oxygen is the main cause of aging in cells. To counter this, nature uses an enzyme called superoxide dismutase to ...

Cytochrome P450 enzymes constitute a superfamily of haem-containing proteins that catalyse the oxidation of a wide range of exogenous and endogenous compounds. Their function is fundamental to the ...

Annotations of enzyme function provide critical starting points for generating and testing biological hypotheses, but the quality of functional annotations is hindered by uncertain assignments for ...