This new review article highlights the pivotal and paradoxical role of R-loops in maintaining genomic stability while simultaneously posing risks to it. These three-stranded nucleic acid structures, ...

(Medical Xpress) -- Researchers at the University of California, Davis, have figured out how the human body keeps essential genes switched “on” and silences the vast stretches of genetic repeats and ...

A new study by researchers at the German Center for Infection Research (DZIF) and Heidelberg University Hospital has identified RNA:DNA hybrids, known as R-loops, as structural features that guide the ...

The DNA inside our cells is constantly being damaged, and one of the worst kinds of damage is a double-strand break—when both ...

Image Caption: The factors contributing to R-loop formation. Several factors contribute to R-loop formation, including RNA components, specific DNA structures, histone and RNA modifications, ...

Researchers have figured out how the human body keeps essential genes switched "on" and silences the vast stretches of genetic repeats and "junk" DNA. Researchers at the University of California, ...