The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

A newly developed luciferase-based reporter can detect problems in protein translocation and disulfide bond formation in the endoplasmic reticulum (ER). Inspired by natural mechanisms found in ...

New research has outlined how cancer cells tolerate chromosomal imbalance by boosting production of the proteins the missing ...

A so-called pathological protein long associated with Parkinson's disease has been found in a new study to trigger cells to increase protein synthesis, an event that eventually kills the subset of ...

Translation factors eIF1A and eIF5B are key repressors of an abnormal protein translation process linked to neurodegenerative ...

Proteins that trigger cell senescence occupy much of the literature on aging, but a small RNA moves into the limelight. Further investigation into SNORA13 revealed that it modifies RNA bases in the ...

One of the hallmarks of cancer cells is their ability to evade apoptosis, or programmed cell death, through changes in ...

As we age, the composition and function of proteins in the brain change, affecting how well our brain performs later in ...

The U.S. commercial launch of LYMPHIR (denileukin diftitox-cxdl), a novel cancer immunotherapy for adults with relapsed or ...