Poly ADP-ribose polymerase inhibitors (PARPi) are used for patients with advanced prostate cancer bearing alterations in homologous recombination repair (HRR) genes. We sought to characterize HRR gene ...
Identification of variants influences treatment decisions. Inhibitors of the poly-ADP-ribose polymerase (PARP) system, a pathway for repairing single-stranded DNA breaks, are recommended for tumors ...
Endogenous Tumor Suppressor microRNA-193b: Therapeutic and Prognostic Value in Acute Myeloid Leukemia The article by Abida et al, entitled "Targeting DNA Repair in Prostate Cancer" (J Clin Oncol ...
Genetic studies of prostate cancer susceptibility have predominantly focused on non-Hispanic white men, despite the observation that Black men are more likely to develop prostate cancer and die from ...
Please provide your email address to receive an email when new articles are posted on . In this video, Tanya Dorff, MD, head of the genitourinary cancers program at City of Hope, discusses data from ...
Image showing polymerase theta and polymerase delta's physical association. CHAPEL HILL, N.C. – Our DNA is not indestructible. Throughout the course of our lives, DNA can break in response to natural ...
Orthocell Ltd has announced the increasing adoption of its product, Remplir™, among Australian urologists for nerve-sparing prostate cancer surgeries, with approximately 100 surgeries conducted ...
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