Researchers used extensive single-cell analysis to create a spatial map of tumor-infiltrating B cells and plasma cells in early-stage lung cancers, revealing new roles for these immune cells in cancer ...
The triangles represent the histological spectrum in the hyaline vascular and plasma cell variants of CD. Percentages for some CD subtypes are not available. CD, Castleman disease; HHV8, human ...
Researchers show for the first time that engineered human plasma B cells can be used to treat a disease—specifically leukemia—in a humanized animal model. The results mark a key step in the ...
SHANGHAI, Oct. 19, 2025 /PRNewswire/ -- Primary plasma cell leukemia (pPCL) is a rare and highly aggressive plasma cell malignancy, often associated with complex genetic abnormalities. There is ...
Plasma cell leukemia (PCL) is a rare, aggressive subtype of multiple myeloma. Between 1973 and 2009, it’s estimated that PCL made up 0.6 percent of multiple myeloma diagnoses in the United States.
cfDI index was assessed on 38 plasma samples collected from as many patients at t2, maintaining a 30/70 ratio between pCR and non-pCR patients. cfDI index showed an area under the receiver operating ...
Many symptoms of multiple myeloma (MM) overlap with other conditions, including low back pain, diabetes, chronic kidney disease and arthritis. Renal insufficiency caused by MM can be difficult to ...
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