The human CD81 (hCD81), the most recently proposed receptor of hepatitis C virus (HCV), can especifically bind to HCV envelope glycoprotein 2 (E2). In this study, hCD81-expressing murine NIH/3T3 cells ...

The recently published recommendations of the European Commission Joint Research Centre (JRC) shine a spotlight on the versatility and scientific benefits of universal antibody libraries in ...

Phage display is an analytical technique used to study protein-protein interactions and the relationship between a protein and the encoding DNA. Phage display begins by incorporating the protein of ...

Anna Munke, Jonas Persson, Tanja Weiffert, Erwin De Genst, Georg Meisl, Paolo Arosio, Anna Carnerup, Christopher M. Dobson, Michele Vendruscolo, Tuomas P. J. Knowles, Sara Linse Proceedings of the ...

Recent advances in phage display for molecular evolution incorporate deep sequencing to enable greater library coverage. However, severe gaps and limitations associated with next generation sequencing ...

Chimeric proteins combine multiple polypeptides that are not normally covalently linked into a single molecular entity in which each functional domain contributes to overall activity. They are ...

Mapping the individual amino acids where antibodies bind (epitopes) to target viral proteins (antigens) is crucial to predicting how target proteins may evolve to escape antibody binding, improve ...

The use of surface plasmon resonance to characterize protein:protein interactions is well established and has been the method of choice for determination of antibody affinity for the last 20 years.

Sanofi-aventis also Licenses Phase 1 Drug Candidate from Merrimack Pharmaceuticals, a Dyax Licensee CAMBRIDGE, Mass.--(BUSINESS WIRE)--Oct. 13, 2009-- Dyax Corp. (NASDAQ: DYAX) announced today new ...

The term lysogenic refers to the ability of bacteriophages to assume a dormant state, referred to as a prophage, in the bacterial cell. Lysogeny is characterised by the integration of the viral DNA ...