Osteocytes are differentiated osteoblasts that live within the bone matrix and are highly connected among themselves and with cells on the bone surface and the bone marrow The molecular and functional ...

This is a preview. Log in through your library . Abstract Skeletal fragility in the elderly does not simply result from a loss of bone mass. However, the mechanisms underlying the concurrent decline ...

A recent discovery could transform our understanding of bone health maintenance and pave the way for potential treatments for bone diseases, including osteoporosis. Researchers at the University of ...

Embedded within bone tissue are osteocytes, cells with tree-like projections called dendrites that are important for receiving communication from other cells. The loss of dendrites that occurs during ...

Researchers have revealed that RANKL expressed by osteocytes is essential for the bone remodeling during orthodontic tooth movement. This result can facilitate the development of novel therapeutic ...

The force gravity and physical activity put on our bones causes tiny tears in the membranes of the tiny cells that enable us to make or break down bone, scientists say. While that may sound bad, it's ...

However, the role of osteocytes-mature bone cells derived from osteoblasts-in OI pathogenesis remains unclear. Specificity protein 7 (Sp7), encoded by Sp7 gene is an important transcription factor ...

Researchers may be "excyted" to learn that osteocyte cultures are headed to the International Space Station this spring for the first time. With their delivery on the next SpaceX commercial resupply ...

Osteogenesis imperfecta (OI) refers to a group of rare genetic bone disorders that results in the formation of fragile bones. In patients with OI, the matrix that makes up the bone has been found to ...