Figure 1: Signal distribution and nucleosome position analysis in the androgen receptor and FOXA1 binding regions identified by ChIP-chip experiments and the TSS. Figure 2: qPCR validation of the ...
Post-translational modifications of the histone tails are correlated with distinct chromatin states that regulate access to DNA. Recent proteomic analyses have revealed several new modifications in ...
The DNA in the cell nuclei of higher organisms is tightly coiled around protein complexes called nucleosomes, which repress gene expression. Researchers in Germany have now developed a model that ...
Proceedings of the National Academy of Sciences of the United States of America, Vol. 74, No. 7 (Jul., 1977), pp. 2780-2784 (5 pages) When histones in chromatin core particles were crosslinked with ...
Researchers at The University of Texas MD Anderson Cancer Center have shown that DNA inflexibility, or rigidity, inside the ...