In the past decade, nucleic-acid-based drugs have become firmly established as a therapeutic modality. Drugs in two classes have now reached the market for multiple diseases—antisense oligonucleotides ...

Researchers from IOCB Prague have discovered a new type of substances capable of safely transporting various types of nucleic acids used for therapeutic purposes into cells, from basic building blocks ...

SINGAPORE – The Nucleic Acid Therapeutics Initiative (NATi), a national platform hosted by the Agency for Science, Technology and Research (A*STAR), officially launched the non-GMP NATi mRNA ...

During translation, multiple ribosomes travel along the nucleic acid chain to build polypeptides that become functional proteins. Occasionally, these molecular decoders pause on the mRNA, either ...

Over three decades, Katalin Karikó had such a hard time obtaining funding for her research into messenger RNA (mRNA) that she was let go from research jobs four times; she once risked deportation ...

Lipid-based nanoparticles (LNPs) are effective non-viral vectors for delivering messenger RNA products (mRNA), most notably used for vaccine production against the recent SARS-CoV-2 pandemic. In this ...

Deborah Fuller is co-founder of Orlance, Inc, a biotechnology company developing a needle free technology to deliver RNA and DNA vaccines. She also serves as a scientific advisor for HDT Bio, a ...

In the early 1990s, direct injection of nucleic acids (RNA or DNA) into the muscles of mice led to in vivo expression of proteins encoded by the injected nucleic acid. 1 This finding, together with ...

All cells on Earth are enveloped in a fatty layer of lipids. Lipid membranes protect the content of the cells, including genetic information such as RNA and DNA. A new study reveals how lipids and RNA ...

Two biotechs are teaming up to deliver cholesterol-busting mRNA to clogged arteries. Syracuse, New York-based Repair Biotechnologies will use Swiss company Genevant’s lipid nanoparticles to usher its ...

SAN DIEGO--(BUSINESS WIRE)--Maravai LifeSciences, Inc. (NASDAQ: MRVI), a global provider of life science reagents and services to researchers and biotech innovators, announced that it has signed an ...