A new study, led by Prof. Liu from the department of pharmacy, University of Electronic Science and Technology of China, discovered that the extracellular cell matrix (ECM) could induce the drug ...

Schematic diagram depicting the mechanism of the rigid matrix regulating cell glycolysis in degenerated NPCs. In degenerated NP tissue, MRTF-A was activated by increased matrix stiffness and ...

A preconditioning method for the finite element stiffness matrix is given in this paper. The triangulation is refined in a subregion; the preconditioning process is composed of resolution of two ...

The research, published in Developmental Cell, is the first to show how local cells sense and respond to changes in basement membrane stiffness caused by damage—and how they activate a previously ...

Researchers in the United States and Japan have discovered a new mechanism that links age-related cartilage tissue stiffening with the repression of a key protein associated with longevity, and the ...

(Nanowerk News) Imagine a world inside your body where tiny cells are like workers building and repairing tissue structures. They interact with their surroundings, which include a scaffold called the ...

Animal cells in tissues are supported by biopolymer matrices, which typically exhibit highly nonlinear mechanical properties. While the linear elasticity of the matrix can significantly impact cell ...