Heart failure is a complex clinical syndrome affecting around 70 million individuals globally. It has a prevalence of 2% in ...

Background Cancer survivors have an increased risk of heart failure, but this is balanced by the risk of death from other ...

Degenerative aortic stenosis (AS) has become the most common valvular heart disease and the definitive treatment of symptomatic, severe AS is surgical valve replacement. In the absence of symptoms, ...

Vasodilators are considered to be contraindicated in patients with severe aortic stenosis because of concern that they may precipitate life-threatening hypotension. However, vasodilators such as ...

Objective: To provide an overview of heart failure with preserved ejection fraction (HFPEF), as well as its pathophysiology, diagnosis, and clinical evidence regarding its pharmacologic management.

Patients with signs and symptoms of heart failure and a normal left ventricular ejection fraction are said to have diastolic heart failure. It has traditionally been thought that the ...

Ejection fraction is a measurement doctors can use to help diagnose heart failure. A normal range is between 52% and 72% for males and between 54% and 74% for females. An ejection fraction that’s ...

Ejection fraction (EF) measures how well the heart pumps blood. A normal EF is 55% to 70%, meaning the heart pumps out at least half of the blood in its left ventricle with each beat. An EF below 50% ...

Chronic heart failure is a syndrome, not a specific disease, and occurs as a final common pathway in multiple disease states. The pathophysiology of chronic heart failure (HF) exists when either the ...

End-diastolic volume is the amount of blood that is in the ventricles before the heart contracts. Doctors use end-diastolic volume to estimate the heart’s preload volume and to calculate stroke volume ...