Severe acute respiratory syndrome virus 2 (SARS-CoV-2), the causative agent of coronavirus disease 19 (COVID-19), uses its spike (S) glycoprotein to enter host cells. The S glycoprotein consists of ...

Sialic acids, also referred to as neuraminic acids, are critical to glycoprotein bioavailability, function, stability, and metabolism. When present, these carbohydrates occupy terminal positions of ...

To investigate whether the amlodipine derivatives, CJX1 and CJX2, have a modulative effect on P-glycoprotein (P-gp) function in rat brain microvessel endothelial cells (RBMEC). Isolated RBMEC were ...

Thanks to a decadelong synthetic push, chemists finally have access to a homogeneous version of the blood-cell-producing glycoprotein erythropoietin (EPO). The product carries carbohydrates at the ...

Retrospective analyses in non-randomised cohorts suggest that regimens containing fludarabine/Ara C and/or idarubicin/ara C may be more effective than daunorubicin/AraC (DA)-containing regimens in ...

Defining blast characteristics in relapsed childhood acute lymphoblastic leukemia using gene expression profiling No significant financial relationships to disclose. This is an ASCO Meeting Abstract ...

A team of US-based scientists has recently demonstrated the cryo-electron microscopic structure and antigenicity of the attachment glycoprotein of the Nipah virus. The study is published in the ...

This is a preview. Log in through your library . Abstract Glycoprotein (GP) V is a major substrate cleaved by the protease thrombin during thrombin-induced platelet activation. Previous analysis of ...

Proceedings of the National Academy of Sciences of the United States of America, Vol. 76, No. 7 (Jul., 1979), pp. 3343-3347 (5 pages) We have investigated the role of the carbohydrate moiety in the ...

Patients with nonvalvular atrial fibrillation and normal kidney function had increased bleeding risk with dabigatran when used alongside P-glycoprotein inhibitors diltiazem and verapamil, according to ...