- Superior and stronger suppression of ETS2 signaling: At all doses, PAS-004 showed greater downregulation of ETS2-regulated genes than selumetinib. - Suppression of core macrophage functions: PAS-004 ...
-- Demonstrates PAS-004’s potential as a differentiated MEK inhibitor for immune-mediated inflammatory diseases such as IBD and ankylosing spondylitis – -- Positions PAS-004 for potential expansion ...
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