This article examines some of the cell-based approaches that researchers are using to study acquired drug resistance and the effects of specific genetic variants on cancer cell physiology.

Cell line development (CLD) follows a process that has only changed slightly since it was established in the early days of biopharmaceutical development. The steps to create a stable, manufacturing ...

Lymphocytosis and smudge cells are characteristic signs of chronic lymphocytic leukemia. They can also be signs of conditions such as other cancers, infections, and autoimmune diseases. Lymphocytosis ...

Gene therapies offer incredible promise for treating diseases with a genetic component. Several gene therapies are already available, and adeno-associated virus (AAV) has become a popular choice for ...

Viral vector-based gene therapies hold immense promise for treating a multitude of diseases. However, their widespread adoption has been hindered by inefficient manufacturing methods and the absence ...