The regulation of the cell cycle is a fundamental process ensuring the accurate replication and division of cells. Central to this regulation are the Cdc25 phosphatases, which activate ...

The awe-inspiring process of cell division can turn a fertilized egg into a baby – or a cancerous cell into a malignant tumor. With so much at stake, nature keeps it tightly controlled in a process ...

When cells proliferate, genomic DNA is precisely duplicated once per cell cycle. Abnormalities in this DNA replication process can cause alterations in genomic DNA, promoting cellular ageing, cancer, ...

"The prize recognizes the confluence of two different approaches to learning about the molecular machinery regulating the cell cycle," says Ira Herskowitz, professor in the department of biochemistry ...

New research has uncovered a surprising link between a tiny cellular engine and the way cancer cells build the DNA they need ...

TGFβ/ACTIVIN-SMAD2/3-EZH2 cooperates with OCT4 and NANOG in self-renewing hPSCs to keep CDKIs in an epigenetically poised state for rapid activation. Upon the initiation of endoderm differentiation ...

There are tens of trillions of cells in the human body, and new cells are constantly forming as older cells age and die. But sometimes, cell growth and replication doesn't stop when it should. These ...

Findings expand Telomir-1's oncology profile into cancers of the blood, adding to previously reported activity in ...