If you can't delete an ISO file as the file is open in your System, check if it is mounted as a drive or not. Uses these proven fixes to resolve the issue.

If you cannot delete a file or a folder on an NTFS file system volume in Windows, follow the solutions mentioned in this post to resolve the issue.

If you're trying to delete a Mac app but can't because it's still open, don't worry! There are a few ways to fix this issue.

Fire up process explorer and find the file is in use by, wait for it, Windows explorer. So Windows Explorer can't rename/move my file because it's in use by itself.

I am in the process of cleaning up my hard drives. I'm having a problem deleting a file in my old Temp. Internet Files folder from a previous Windows installation.The file is called TILE\\1~1,JPG ...