CAMBRIDGE, Mass. (September 27, 2012) – For a cancer patient, over-expression of the MYC oncogene is a bad omen. Scientists have long known that in tumor cells, elevated levels of MYC's protein ...

Longitudinal monitoring of BRAF V600E mutation in urinary cell-free DNA of patients with metastatic cancers. This is an ASCO Meeting Abstract from the 2014 ASCO Annual Meeting I. This abstract does ...

The c-Myc oncoprotein is frequently overexpressed in human cancers and is essential for cancer cell proliferation. The dysregulation of ubiquitin-proteasome-mediated degradation is one of the ...

Scientists at the Karolinska Institutet in Sweden have found a new region in the c-Myc oncogene that would allow the development of a binding compound to target it. Their discovery is based on a ...

Scientists at Lund University have discovered how E. coli bacteria target and degrade the well-known oncogene MYC, which is involved in many forms of cancer. The study is now published in Nature ...

A promising new treatment to combat "undruggable" cancers has been green-lit for a human trial in 2025. It's hoped the novel drug will be able to stunt the growth and enable the effective treatment of ...

This is a preview. Log in through your library . Abstract Lung cancer is a leading cause of cancer death worldwide; however, despite major advances in cancer treatment during the past two decades, the ...