Animal testing is costly, slow, and poorly predictive. ORIVA offers a human-relevant alternative with the potential to change that.

LaBonne is president of the Society for Developmental Biology and the Erastus Otis Haven professor of molecular biosciences at Northwestern University. Imagine a world without lifesaving medicines, ...

Too often, preclinical successes are followed by clinical failures. And all clinical failures hurt. Perhaps the most painful failures occur in trials that require large patient populations and long ...

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

New computer models predict the risk of side effects from heart drugs more accurately than animal models. Researchers from the University of Oxford (UK) have developed computer simulations that are ...

The Lab Animal Nutrition Core (LAN) was established in 2019 to study, advise, formulate and produce lab animal diets for standard and novel animal models with translation to human health. The LAN is ...

"Rodents are the most widely utilized models in biomedical research...The majority of oncology drugs that proved successful in treating tumors within rodents fail to have the same response in humans, ...