The National Academies of Sciences, Engineering, and Medicine are private, nonprofit institutions that provide expert advice on some of the most pressing challenges facing the nation and world. Our ...

AI and computational modeling are reducing reliance on animal testing by simulating human biology, improving drug safety and efficacy predictions. Regulatory bodies like the FDA and NIH are endorsing ...

Testing new treatments in other animals can help us spot complications or potential pitfalls, but the results don’t always ...

Animal testing is costly, slow, and poorly predictive. ORIVA offers a human-relevant alternative with the potential to change that.

In recent months, the Food and Drug Administration and National Institutes of Health have announced new initiatives to reduce and replace animal testing in biomedical research. Central to these ...

Animal models are established, important tools for preclinical safety and efficacy testing. Companies are advancing more “humanized” models to better reflect human responses, while at the same time ...

Despite an FDA green light for the use of animal testing alternatives in drug development, regulatory concerns may be keeping the industry from embracing them, data collected by the R&D organization ...

Early on in the pandemic, it became clear Covid-19 had made the leap from animals to humans. The exact chain of transmission isn't known, but the science so far suggests bats played a starring role.