A cancer drug target already being investigated in clinical trials turns out to be doing something even more consequential ...
Discovery reshapes understanding of how tumor cells repair broken DNA, pointing toward more precise cancer therapies.
Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer ...
Researchers at the University of Minnesota Medical School have developed a new method called PARTAGE that provides a clearer picture of how the genome is regulated and disrupted in diseases like ...
When bacteria cells replicate, they do so a little differently than human cells do. They don't undergo mitosis, a splitting that involves construction of spindles to carefully separate the DNA after ...
Researchers discovered a kinase-driven phosphorylation switch that activates DNA packaging machinery, aligning nucleosomes at ...
Top: Chromosome separate with functioning SMC in two models, line drawing and filled-space. The red and pink dots indicate, respectively, ori on each copy of DNA. Bottom: DNA separating without ...
Before a cell can divide, it has to precisely duplicate its entire genetic information. However, the DNA in the cell exists ...