Rapid and extensive Schwann cell death under high-glucose pyruvate-depleted conditions can be evoked by the following sequential metabolic alterations; 1) diminished TCA cycle intermediates and ...
Using a gas chromatography–mass spectrometry (GC–MS) method with stable isotope internal standards, 3 we measured concentrations of sorbitol and its polyol pathway metabolite, fructose, as well as ...
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