Poly(A) tails enhance the stability and translation of most eukaryotic messenger RNAs, but difficulties in globally measuring poly(A)-tail lengths have impeded greater understanding of poly(A)-tail ...

Deadenylation of mRNAs is generally associated with translational inhibition and mRNA decay. A study now reports that, unexpectedly, highly expressed genes tend to have shorter poly(A) tails and ...

Translation efficiency and poly (A) tail length are not linearly correlated and only coupled in limited range, report scientists. This research is, 'helping to build the foundation for further work ...

Before mRNA can be used by ribosomes as a guide to build proteins, it has to undergo a series of processing steps. This includes getting a series of adenine (A) nucleotides added by poly(A) polymerase ...