In a recent study published in Nature Communications, researchers assessed the impact of the gut microbiome on the host's bile acid metabolism and intrahepatic cholestasis of pregnancy (ICP). Study: ...

Please provide your email address to receive an email when new articles are posted on . The FDA has issued a safety alert warning patients and health care providers of a “rare risk of intrahepatic ...

A 41-year-old gravida 5 para 2113 at 32 and 4/7 weeks' gestation presented to labor and delivery with generalized pruritus of 3-days' duration. She had no outward signs of rash or pustules. She also ...

Intrahepatic cholestasis of pregnancy is a reversible form of cholestasis, in genetically predisposed individuals. Onset is late in pregnancy and clinically it is characterized by the presence of ...

Intrahepatic cholestasis of pregnancy is a gestation-specific liver disorder characterised primarily by pruritus and elevated serum bile acid levels, typically manifesting in the second or third ...

A recent study published in Frontiers in Medicine evaluated the effects of coronavirus disease 2019 (COVID-19) quarantine on outcomes in individuals with intrahepatic cholestasis of pregnancy (ICP).

Pregnant patients should discontinue use of thiopurines if they develop intrahepatic cholestasis of pregnancy. The use of thiopurines (eg, azathioprine, 6-mercaptopurine, and 6-thioguanine) by ...

A new study found a strong connection between azathioprine exposure and development of ICP in women with systemic lupus erythematosus (SLE).

A pregnant person with a history of cytomegalovirus and elevated liver function tests presents with relentless, worsening pruritus. A 34-year-old woman presents to her obstetrician at 15 weeks’ ...

Credit: Mirum Pharmaceuticals. The approval was based on data from the phase 3 MARCH-PFIC trial. The Food and Drug Administration (FDA) has approved Livmarli ® (maralixibat) for the treatment of ...