The process of GLUT4 trafficking is central to the metabolic regulation of blood glucose levels. In both muscle and adipose cells, the insulin hormone triggers the mobilisation of intracellular ...

The role of the adapter protein PICALM in the development of Alzheimer's disease is well documented. Researchers from the German Institute of Human Nutrition Potsdam-Rehbruecke (DIfE), the German ...

Insulin is essential for glucose homeostasis and one of its key functions is to drive glucose uptake into adipocytes and myocytes. Insulin’s role in this process became apparent in 1921 and the ...

Researchers at the University of California, San Francisco, and collaborators at Harvard Medical School have linked a specialized protein in human muscles to the process that clears glucose out of the ...

The common forms of type 2 diabetes are caused by a constellation of genetic and epigenetic factors and molecular changes related to diet; lifestyle, including lack of exercise and sleep; ...