Scientists at the Leibniz Institute on Aging—Fritz Lipmann Institute (FLI) in Jena have discovered a previously unknown function of immune cells in the bone marrow. Embryonic macrophages—specialized ...

Sox9, a master regulator of cartilage formation, switches its target genes dynamically during embryonic limb development instead of following a fixed program, as reported by researchers from Science ...

The musculoskeletal system provides structural support, enabling movement such as walking and lifting, protecting internal organs, maintaining posture, generating heat through muscle activity, and ...

Researchers have gained new insights into the mechanism behind the spatial organization of DNA within the cells of early embryos. When an embryo is first formed after fertilization, each cell has the ...

The earliest days after fertilization, once a sperm cell meets an egg, are shrouded in scientific mystery. The process of how a humble single cell becomes an organism fascinates scientists across ...

Using CRISPR-based engineering methods to prompt stem cells to organize into embryo-like structures, scientists were able to create 'programmable' cellular models of embryos without ever experimenting ...

Mechanotransduction—the process by which cells convert mechanical forces into biochemical signals—is now recognised as a fundamental regulator of embryonic morphogenesis. During early development, ...

As an embryo grows, there is a continuous stream of communication between cells to form tissues and organs. Cells need to read numerous cues from their environment, and these may be chemical or ...

Bioengineering researchers at the Harvard John A. Paulson School of Engineering and Applied Sciences (SEAS) have developed a soft, thin, stretchable bioelectronic device that can be implanted into a ...