Chromosome segregation and site-specific recombination are central processes in bacterial cell division and genome maintenance. The orchestration of these events ensures that circular chromosomes are ...

Accurate chromosome segregation and cell division are central to maintaining genomic integrity and ensuring proper development and tissue homeostasis. These processes rely on a complex network of ...

The improper segregation of chromosomes during cell division leads to abnormalities that disrupt the proper functioning of the cell. Cells with an abnormal number of chromosomes consequently activate ...

Centromeres play virtually the same central role across the entire tree of life: They ensure the faithful segregation of chromosomes during cell division. Yet the striking diversity in centromere ...

Advancements in genome sequencing have challenged the long-standing belief that the position of the centromere in the chromosome is fixed. Researchers from Okayama University, Japan, have analyzed ...

For successful cell division, chromosomal DNA needs to be packed into compact rod-shaped structures. Defects in this process can lead to cell death or diseases like cancer. A new study has shown how ...

DLGAP5 is proposed as a causal gene related to oocyte meiosis disorder for the first time. It expanded the current spectrum of pathogenic genes responsible for the phenotype of oocyte maturation and ...

A research team from The University of Osaka, in collaboration with the Massachusetts Institute of Technology, has uncovered a new molecular mechanism underlying chromosome alignment during cell ...

Despite the immense amount of genetic material present in each cell, around three billion base pairs in humans, this material needs to be accurately divided in two and allocated in equal quantities.

Halving of chromosomes occurs during meiosis, a special cell division, but failure leads to the wrong number of chromosomes in the eggs/sperm/pollen, that may cause miscarriages or rare genetic ...

About 50 percent of pregnancies fail, and one of the main reasons is aneuploidy, a genetic condition in which cells do not have the correct number of chromosomes. 1 Aneuploidy commonly arises when ...