ascopubs.org

BIM deletion polymorphism and the clinical outcome of patients with advanced NSCLC who received first-line platinum-based chemotherapy: Preliminary results.

Correlation between biopsy type and insufficient tissue availability for biomarker testing in five solid cancer types. This is an ASCO Meeting Abstract from the 2013 ASCO Annual Meeting I. This ...
Nature

HSPB1 facilitates ERK-mediated phosphorylation and degradation of BIM to attenuate endoplasmic reticulum stress-induced apoptosis

BIM, a pro-apoptotic BH3-only protein, is a key regulator of the intrinsic (or mitochondrial) apoptosis pathway. Here, we show that BIM induction by endoplasmic reticulum (ER) stress is suppressed in ...