Folate can be “normal” in blood—and low in the brain. Kids with cerebral folate deficiency may have folate receptor antibodies that block transport into the brain. Result: normal serum, low CSF, and symptoms tied to impaired neurotransmitter production. In today’s episode, pediatric neurologist Dr. John Gaitanis breaks down: How folate actually gets into the brain (and why transport matters) Why some kids regress or develop tics/OCD despite “normal” labs Practical steps families and clinicians c
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Folate can be “normal” in blood—and low in the brain. Kids with cerebral folate deficiency may have folate receptor antibodies that block transport into the brain. Result: normal serum, low CSF, and symptoms tied to impaired neurotransmitter production. In today’s episode, pediatric neurologist Dr. John Gaitanis breaks down: How folate actually gets into the brain (and why transport matters) Why some kids regress or develop tics/OCD despite “normal” labs Practical steps families and clinicians c
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🧠 Did you know many kids with autism have low folate in their brains…even when blood tests look normal? It’s called Cerebral Folate Deficiency (CFD), a treatable condition where folate can’t properly cross into the brain. Folate (vitamin B9) is essential for DNA, RNA, and energy production — so when the brain is low, it affects mood, movement, and development. Here’s what research shows: ⚡ 71% of autistic kids have folate receptor autoantibodies (FRAAs) — these block folate from entering the br
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