John Kempen, MD, MPH, PhD, MHS, Director of Epidemiology for Ophthalmology at Mass Eye and Ear and Harvard Medical School, is ...

Randomized clinical trials remain the gold standard for establishing a medication's effects, producing the evidence by which ...

Introduction Each year, millions of people experience recurrent diverticulitis episodes. Elective sigmoid colon resection reduces the risk of recurrence, but The American Society of Colon and Rectal ...

Large language models could transform digestive disorder management, but further RCTs are essential to validate their ...

A New York Times health reporter explains what clinical trials are, why they are important and how they can help inform us. Credit...Ricardo Tomás Supported by By Nina Agrawal Nina Agrawal is a health ...

Orforglipron, a small-molecule, nonpeptide oral glucagon-like peptide-1 (GLP-1) receptor agonist, is being investigated as a treatment for obesity. In this phase 3, multinational, randomized, ...

“Well, we don’t have as much evidence as we would like on steroid use during pregnancy,” the obstetrician warned my co-author, Natalia Emanuel, as she wrote a prescription for inhaled corticosteroids ...

Introduction: Children and young people with Attention Deficit Hyperactivity Disorder (ADHD) face disproportionate challenges due to core symptoms of ADHD (i.e., inattention and hyperactivity) ...

Objectives Authentic patient and family engagement in child health research is defined as researchers working in partnership with patients and families on all aspects of the research process, ...

Patients undergoing cardiac surgery often receive red-cell transfusions, along with the associated risks and costs. Early intraoperative normovolemic hemodilution (i.e., acute normovolemic ...

New vaccines are often evaluated in trials in which some participants receive a placebo. But not all studies can be designed this way. By Teddy Rosenbluth The Department of Health and Human Services ...