AZoLifeSciences on MSN

New method turns glial cells directly into parvalbumin neurons

Parvalbumin cells play a central role in keeping brain activity in equilibrium. They control nervcell signaling, reduce ...

Creating cells that help the brain keep its cool

Researchers at Lund University in Sweden have created a method that makes it possible to transform the brain's support cells ...
Frontiers

Metabolic reprogramming in bone metastasis of human cancers

Bone metastasis represents a complex complication of advanced human malignancies. Metabolic reprogramming plays a critical role in bone metastasis. Tumor cells hijack and alter local metabolic ...
Observer

This Longevity Startup Is Bringing Anti-Aging Gene Therapy to Human Trials

Boston-based Life Biosciences is testing whether reprogramming human cells can slow or even reverse the effects of aging. Unsplash Life Biosciences, a Boston-based biotechnology company founded in ...
eLife

Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

The findings of this important study substantially advance our understanding of the transcription factors that can induce hair cell-like cells from human pluripotent stem cells. The presented evidence ...
eLife

Inducible, virus-free direct lineage reprogramming enhances scalable generation of human inner ear hair cell-like cells

The POU4F3-tdTomato hair cell reporter becomes visible after ∼3 days of reprogramming. Representative images were acquired at 0-, 3- or 7-days post-doxycycline treatment. Scale bar represents 200 µm.
Business Wire

Seamless Therapeutics to Present New Data at ESGCT Demonstrating its Ability to Reprogram Large Serine Recombinases to Specific Target Sites in the Human Genome

DRESDEN, Germany & LEXINGTON, Mass.--(BUSINESS WIRE)--Seamless Therapeutics today announced that it will be presenting new preclinical data, including human cell data, highlighting its unique platform ...