Nature

DNA microarrays in drug discovery and development

Most pharmaceuticals sold today have their origin in a biochemistry laboratory. Drug discovery has traditionally started with a biochemical pathway implicated in a pathophysiological process. An ...
Nature

Microarray fabrication with covalent attachment of DNA using Bubble Jet technology

Here we present a method for the fabrication of microarrays in which presynthesized oligonucleotides are ejected onto a glass surface by a Bubble Jet printing device. The oligonucleotides are then ...
Frontiers

Integration of chromosomal microarray analysis and whole-exome sequencing for prenatal diagnosis of fetuses with cardiac ultrasound anomalies

Background: Congenital heart disease is among the most prevalent birth defects. This study aims to evaluate the clinical utility of chromosome microarray analysis (CMA) and whole-exome sequencing (WES ...
C&EN

Design of Recombinant Antibody Microarrays for Cell Surface Membrane Proteomics

Deptartment of Immunotechnology, BMC D13, Lund University, SE-221 84 Lund, Sweden, CREATE Health, BMC D13, Lund University, SE-221 84 Lund, Sweden, and Bioinvent International AB, SE-223 70 Lund, ...
IEEE

Convex Microarrays-Based Liquid Metal Soft Piezoresistive Stress Sensor With High Sensitivity and Large Measurement Range

Abstract: Liquid metal (LM) soft piezoresistive sensors, that is, devices that change resistance in response to mechanical forces, have low hysteresis and high stability, which exhibit great promise ...
Frontiers

Digital atlas of anatomical subdivisions and boundaries of the rat hippocampal region

The rat hippocampal region is frequently studied in relation to learning and memory processes and brain diseases. The region is complex, consisting of multiple subdivisions that are challenging to ...