Patients with SSc were linked to an increased risk for hematological malignancies, specifically B-cell malignancies.

Background Systemic sclerosis, also known as scleroderma, is a complex, multi-organ disease which causes substantial and progressive fibrosis of the skin and internal organs, including the heart and ...

Based on real-world clinical data from 40 IgAN patients at Baise People’s Hospital, this study systematically analyzed the correlation between the Oxford Classification and other pathological features ...

Scleroderma is an autoimmune condition that causes the skin to become tight and hard. This can change facial appearance, such as the mouth becoming smaller, and affect internal organs. With ...

Roche has reported wins for its BTK inhibitor fenebrutinib in a pair of phase 3 studies across two multiple sclerosis (MS) populations. One victory was based on the finding that the candidate was ...

In the human brain, neurofilament light chain (NfL, shown in brown) is seen in brain cells and the neural wires that connect them. UCSF researchers found NfL in the bloodstream of patients who would ...

Objective To determine the distribution of the EULAR SSc Impact of Disease (ScleroID) and its domain questions in very early (Ve), limited (lc) and diffuse cutaneous (dc) subsets, its value in ...

Sheffield Teaching Hospitals NHS Foundation Trust has become the only site in the UK to open a groundbreaking international ...

Changes in NAWM and NAGM are crucial in MS progression, challenging the traditional lesion-centric model. Subtle alterations in myelin integrity, immune cell function, and neuronal connectivity ...