Comprehensive map reveals how E3 ligases organize protein cleanup in human cells

Individual mammalian cells contain billions of protein molecules, which must be synthesized, deployed, and removed with ...

How cholera virulence is activated: A long-sought structural explanation

Cholera remains a major global public health challenge, with an estimated 1.3 to 4 million cases and tens of thousands of ...
IEEE

Crowd Density Estimation Using Enhanced Multi-Column Convolutional Neural Network and Adaptive Collation

Abstract: Accurate crowd density estimation is essential for public safety operations, urban and transportation design and multiple intelligent systems. The research presents an improved Multi-Column ...
IEEE

Multi-Objective Structure-Based Drug Design Using Causal Discovery

Abstract: Structure-based drug design (SBDD) is a critical subtask in the drug discovery process, with deep generative models playing a pivotal role. Inherently, drug design is a multi-objective task ...
GitHub

Inverse Design of Joints Section

The digit portions were mapped to steel, while the remaining portions were mapped to concrete. Figure illustrates the relationship between the proportion of steel in the cross-section and the strength ...