The ubiquitin/proteasome-dependent proteolytic pathway is an attractive target for therapeutics because of its critical involvement in cell cycle progression and antigen presentation. However, ...
Pro-IL-16 is a 631 amino acid precursor molecule 1,2, which can be cleaved by caspase into two parts. The N-terminal part is kept in the cytoplasm 3, and the C-terminal is a secreted peptide ...