Each year 29 June marks World Scleroderma Day. This article highlights the symptoms, latest research and a genuine ‘diary’ experience from a US patient. The date 29 June was chosen to raise awareness ...

The anti-interleukin agent romilkimab showed significant benefits on skin fibrosis among patients with systemic sclerosis in a phase II trial, researchers reported. At week 24, the least squares mean ...

Substantial evidence exists that patients with scleroderma have immune dysfunction and autoimmunity, and several studies support the use of immunosuppressive treatment in these patients. Nihtyanova et ...

Scleroderma interstitial lung disease (SLD) is a leading cause of morbidity and mortality in patients with systemic sclerosis. Although the pathogenesis of SLD is not clear, excessive fibrosis and ...

Calcinosis circumscripta (CC) is a benign lesion characterized by focal-to-multifocal mineralized deposits mainly in the cutaneous and subcutaneous tissues. CC is uncommon in the oral cavity of dogs ...

Background Calcinosis cutis (CC) is a rare disorder characterized by the abnormal deposition of calcium salts in the subcutaneous tissues of patients with normal calcium metabolism. Dystrophic ...

Gastrointestinal (GI) involvement is almost universal in patients with systemic sclerosis (SSc) and is associated with significant disease-related morbidity and mortality.1 The entire GI tract can be ...

Indurated skin is a deep thickening that can feel firm and may look shiny. Skin infections like abscesses and inflamed cysts can cause indurated skin. Treatment of indurated skin depends on the cause ...