The Schwann cell precursor (SCP) represents the first step in the process of gliogenesis in growing nerves. In addition to generating Schwann cells, these cells are likely to provide essential trophic ...
Researchers identify two key proteins that allow chandelier cells to connect with excitatory neurons. This "handshake" regulates brain signals and, when disrupted, may lead to epilepsy or autism.
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ALS breakthrough: Restoring protein production in motor neuron axons
Researchers at VIB and KU Leuven have identified a molecular process that allows motor neurons to maintain protein production, a process that fails in amyotrophic lateral sclerosis (ALS).
Prefoldin 5 stabilises neuronal microtubules and suppresses Tau-mediated neurotoxicity, offering a potential therapeutic target for tauopathies.
The postsynaptic density (PSD) of excitatory synapses is a membrane-associated mega-organelle that is highly enriched in glutamate receptors and their downstream signalling proteins. Scaffold proteins ...
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