A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

CAR T-cell therapy can be a lifesaving treatment for blood cancers like leukemia and lymphoma. The gene therapy trains a ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and ...

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

Using AI, scientists have built a “GPS” for cancer-fighting immune cells. It’s a molecular navigation system that helped the cells lock onto cancer, kind of like Google Maps guiding travelers to a new ...

Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a ...