A paper published in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key driver in ...

A new paper published today in Cell highlights how researchers have leveraged AI-based computational protein design to create a novel synthetic ligand that activates the Notch signaling pathway, a key ...

A newly revealed molecular tug-of-war may have implications for better understanding how a multitude of diseases and ...

A hidden “jack-in-the-box” mechanism inside T cells may hold the key to unlocking more powerful cancer immunotherapies.

To enhance CAR T therapies, scientists are actively studying TCR signaling and T-cell exhaustion mechanisms to improve CAR T persistence and function. Additionally, there is a growing trend towards ...

Using AI, scientists have built a “GPS” for cancer-fighting immune cells. It’s a molecular navigation system that helped the cells lock onto cancer, kind of like Google Maps guiding travelers to a new ...

The average human cell contains roughly 10,000 different proteins. Existing as several to millions of copies in each cell, proteins mediate all manner of tasks, including chemical transformations, ...

Researchers at UT Southwestern Medical Center have identified a protein that causes human cell membranes to break open in a ...