Nature

Left ventricular global systolic dysfunction has a significant role in the development of diastolic heart failure in patients with systemic hypertension

Whether left ventricular (LV) systolic properties are reduced in diastolic heart failure (DHF) remains controversial, because patients with DHF maintain a normal stroke volume and ejection fraction ...
Medscape

Systolic and Diastolic Left Ventricular Dysfunction: From Risk Factors to Overt Heart Failure

Because life expectancy and the prevalence of risk factors such as hypertension, obesity and diabetes are rising globally, heart failure (HF) is growing into a major health problem. Impairment of left ...
AHA/ASA Journals

SREBP1 Transactivation of NHE3 Impairs Cardiac Contraction and Aggravates Heart Failure

BACKGROUND: Heart failure with reduced ejection fraction (HFrEF) is characterized by impaired contractility and high ...
Nature

Relations of left ventricular mass and systolic function to endothelial function and coronary flow reserve in healthy, new discovered hypertensive subjects

Left ventricular hypertrophy (LVH) is prognostically relevant, associated with major cardiovascular risk factors and with atherosclerosis. However, whether LVH is independently associated with ...
Medscape

What To Do With Diastolic Heart Failure (Preserved Systolic Function)? Results of the PEP-CHF Trial

PREAMI, which showed benefit in terms of LV remodeling in post-MI patients with HF and preserved systolic function -- the results of PEP-CHF supporting the treatment of these patients with an ACE ...
BMJ

Left ventricular systolic function and diastolic filling after intermittent high intensity team sports

Background: Prolonged steady state exercise can lead to a decrease in left ventricular (LV) function as well as promote the release of cardiac troponin T (cTnT). There is limited information on the ...