New hifiasm-ONT assembly method delivers high-quality, cost-efficient near T2T assemblies using standard Oxford Nanopore Simplex reads, broadening access to comprehensive genome assemblies across ...

Simplex optimization is one of the simplest algorithms available to train a neural network. Understanding how simplex optimization works, and how it compares to the more commonly used back-propagation ...

These criteria are useful when you want to divide a time-consuming optimization problem into a series of smaller problems. Since the Nelder-Mead simplex algorithm does not use derivatives, no ...