Scientists can peer into cells to get a limited view of their activity using microscopes and other tools. However, cells and ...
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RNA splicing and processing genes emerge as central drivers of aging across tissues
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled "A combination of differential expression and network connectivity analyses ...
Gene expression analysis and RNA sequencing have transformed our understanding of molecular biology, offering a comprehensive view of transcriptomic landscapes in diverse biological systems. By ...
Explore RNA interference methods, comparing siRNA and shRNA for gene knockdown, their mechanisms, advantages, and ...
Our results demonstrate that differential connectivity analysis reveals significant transcriptional alterations that are not ...
The advent of the spatial omics era has enabled researchers to acquire vast amounts of transcriptomics and proteomics data. The abundance of a transcript, however, does not necessarily display strong ...
An alternative splicing regulator previously implicated in calcium signaling in the heart ensures cell-type-specific mRNA processing of long neuronal mRNAs in the mouse brain.
Ancient DNA has been pulled from a permafrost-preserved woolly mammoth found in Siberia, and scientists are thrilled. They ...
Scientists are consistently one-upping each other when it comes to finding the oldest molecules from fossils. The race even includes the notoriously fragile RNA. “It’s groundbreaking,” said Oliver ...
A new research paper featured as the cover of Volume 17, Issue 12 of Aging-US was published on December 22, 2025, titled “A combination of differential expression and network connectivity analyses ...
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