Retinitis pigmentosa (RP) is a genetic eye disorder affecting around one in 5,000 people worldwide. It typically begins with ...

The creation of memories in the brain involves addition or removal of methyl groups at precise spots on chromosomal DNA. But what controls the careful targeting of these neuronal DNA methylation ...

In patients with retinitis pigmentosa (RP), crucial cells in the retina known as rods and cones die over time; night ...

The expression of genes has to be very carefully controlled by cells; serious problems can arise when genes are expressed in the wrong places, at the wrong times, or at the wrong levels, for some ...

Understanding glioblastoma survival: A SEER-based study of demographics and treatment. Real-world experience with vorasidenib in IDH-mutant gliomas: Tolerability, adverse events, and access in ...

In RNA molecules, the 5′ untranslated region (UTR) is located directly upstream of the start codon and plays a crucial role in post-transcriptional regulation by controlling RNA stability, cellular ...

IOB researchers, in collaboration with a team from Radboud University Medical Center and partners from more than 100 institutions worldwide, identify new genetic cause of inherited blindness. The ...

Digital spatial profiling of advanced solid tumors and lymphomas from a phase 1 trial of copanlisib and nivolumab. Using single-cell sequencing to identify endothelial expression of immune checkpoint ...