New research reveals that subtle chemical changes to proteins after synthesis play a critical role in determining drug-protein interactions.

Respiratory infections, pink eye, or an upset stomach may seem like unrelated, mild inconveniences, but all of these ailments share one root cause: adenovirus infection. Many of us will encounter some ...

Researchers at Baylor College of Medicine have developed an artificial intelligence (AI) model that reveals how protein modifications link genetic mutations to disease. The method, called DeepMVP and ...

Chemical changes to histones, the proteins that help to pack and organize DNA inside cells, play a key role in determining what genes will be consistently activated over the course of an animal or ...

Citrullination, a post-translational modification of proteins catalysed by peptidyl-arginine-deiminase (PAD) enzymes, plays a critical role in the formation ...

This listicle covers the fundamentals and latest innovations in western blotting, including automated workflows, single-cell ...

LA JOLLA, CA—Imagine riding a bike. Now imagine riding a bike with an enormous beach ball stuck on your handlebars. That "modification" might change your experience quite a bit. In our cells, ...

What Are Proteoforms and Why Do They Matter? For decades, scientists assumed that each gene produces just one stable protein. Modern proteomic investigations suggest otherwise. Recent studies have ...