BK and CaV1.3 channels interact early during biogenesis, assembling intracellularly before membrane localization, indicating coordinated processes for functional coupling.

Laboratory cell experiments and computer simulations have revealed molecular mechanisms regulating a protein channel responsible for transporting chloride and other charged molecules across cell ...

For decades it was assumed that protein channels and protein pumps fulfilled completely different functions and worked independently of each other. Researchers have now elucidated the transport path ...