Clinicians often face uncertainty about whether they can rely on a negative chest x-ray (CXR) to rule out pneumonia in a child, even when other clinical signs and symptoms may have raised that concern ...

Objective To review the sensitivity and specificity of the proposed international consensus on-field visible signs of concussion in a cohort of National Rugby League (NRL) players. Design Prospective ...

Human epidermal growth factor receptor 2 (HER2) overexpression is present in about 3% to 5% of cases of metastatic colorectal cancer. HER2 is a well-established negative predictive biomarker in ...

In algorithms, as in life, negativity can be a drag. Consider the problem of finding the shortest path between two points on a graph — a network of nodes connected by links, or edges. Often, these ...

In the article accompanying this editorial, Roschewski et al 1 present a retrospective, observational, multicenter pooled analysis designed to explore the prognostic significance of circulating tumor ...

A blood test based on whole-genome sequencing achieved 99% sensitivity and specificity for detecting HPV-positive head and neck cancer. Early postoperative detection of circulating tumor DNA predicted ...