Dual RPDD and ODD for FL118 in osteosarcoma create regulatory incentives that may accelerate development for a rare, aggressive pediatric/AYA bone cancer with limited recurrent-disease options. FL118 ...

Large-scale analysis of patient cohorts reveals a novel mechanism driving osteosarcoma, an aggressive paediatric bone cancer. The researchers show that this mechanism occurs in approximately 50% of ...

Philadelphia, November 19, 2025 – Researchers at Children’s Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and adolescents. This information ...

A hospital-based antimicrobial stewardship program (ASP) using post-prescription review and feedback (PPRF) significantly decreased intravenous (IV) antibiotic duration, length of hospital stay, and ...

We were unable to process your request. Please try again later. If you continue to have this issue please contact customerservice@slackinc.com. Adolescents with overweight or impaired glucose ...

Researchers at Children's Hospital of Philadelphia (CHOP) revealed important genetic components that affect bone density in children and adolescents. This information could help identify pediatric ...

A pair of proteins could contribute to the development of healthy, strong bones by directing early cell movement and blood vessel generation. A pair of proteins, YAP and TAZ, has been identified as ...

Please provide your email address to receive an email when new articles are posted on . There was a significantly heightened likelihood for fractures among children with vs. without asthma. Those with ...