There are some genes that can promote cancer; they are sometimes called oncogenes, and in tumor cells, mutations are often found in these genes. When they are functioning normally, oncogenes are often ...

Despite progress in defining functional elements of noncoding DNA, it is still not fully understood. UCLA researchers, using an experiment that elucidated the function of tens of thousands of ...

Non-coding DNA is essential for both humans and trypanosomes, despite the large evolutionary divergence between these two species.

(L to R) Co-first author Jackson Mobley, PhD, corresponding author Daniel Savic, PhD, and co-first author Kashi Raj Bhattarai, PhD, all of the St. Jude Department of Pharmacy and Pharmaceutical ...

A research team led by Zhiping Weng, Ph.D., and Jill Moore, Ph.D."18, at UMass Chan Medical School, has nearly tripled the ...

Researchers are investigating the role of non-coding DNA, or junk DNA, in regulating astrocytes, brain cells involved in Alzheimer's disease.

Noncoding elements in the genome, such as enhancers, silencers, and insulators, play important roles in gene expression and thus cellular behavior. Therefore, these elements may be of particular ...

The non-coding genome, once referred to as "junk DNA," is now understood to be a fundamental regulator of gene expression and a key factor in understanding complex diseases. Image credit: ...

Using STING-seq, short for systematic targeting and inhibition of noncoding GWAS loci with single cell sequencing, Sanjana and his team identified promising sequence variants linked to various ...

Imagine the human genome as a string stretching out for the length of a football field, with all the genes that encode proteins clustered at the end near your feet. Take two big steps forward; all the ...