Systemic sclerosis sine scleroderma (ssSSc) affects nearly 10% of patients with systemic sclerosis (SSc), with substantial internal organ involvement. Despite lacking skin fibrosis, patients with ...

CARLSBAD, California — In 2003, researchers asked 303 patients with systemic sclerosis (scleroderma) what bothered them most about their disease from an aesthetic standpoint: Orofacial features, such ...

The scleroderma skin pinch test checks the thickness and elasticity of your skin. It can help doctors diagnose and monitor scleroderma, an autoimmune condition that causes inflammation and thickening ...

Despite current therapies, diffuse cutaneous systemic sclerosis (scleroderma) often has a devastating outcome. We compared myeloablative CD34+ selected autologous hematopoietic stem-cell ...

For the 300,000 Americans living with the immune disease scleroderma, better treatments can't come soon enough. The rare and sometimes fatal illness stiffens and scars tissue in organs like the lungs, ...

The finding of collagenous encapsulation of Brunner's glands and pathological changes in the muscularis mucosae in a duodenal biopsy from a patient with severe progressive systemic sclerosis prompted ...

The anti-interleukin agent romilkimab showed significant benefits on skin fibrosis among patients with systemic sclerosis in a phase II trial, researchers reported. At week 24, the least squares mean ...

Suggested Citation: "4 Scleroderma." National Academies of Sciences, Engineering, and Medicine. 2022. Selected Immune Disorders and Disability. Washington, DC: The ...

Scleroderma is a range of disorders in which the skin and connective tissues tighten and harden. It is a long-term, progressive disease. This means it gradually gets worse. Share on Pinterest ...

Most people with scleroderma have autoantibodies. Several scleroderma-specific antibodies have been identified. These can help with diagnosis and give insight into the type of disease you may ...

Please provide your email address to receive an email when new articles are posted on . Scleroderma and other connective tissue diseases such as systemic lupus erythematosis, dermatomyositis, Behçet’s ...