DNA can also be demethylated, either through passive or active processes. Passive DNA demethylation occurs when the methylation pattern is not replenished during DNA replication and gradually ...

Scientists at the MRC Laboratory of Medical Sciences (LMS) have discovered a DNA-based “dimmer switch” that regulates the activity of a critical developmental gene, Cdx2. This work could pave the way ...

A new study led by researchers at UTHealth Houston investigated both gene expression and regulation at single cell levels to ...

What do your genes have to do with growing old? Quite a lot. But is it due to the actual DNA, or the way those genes are expressed? KPBS sci-tech reporter Thomas Fudge has more on new research that ...

Precision and timing of gene expression is essential for normal biological functions and, when disrupted, can lead to many ...

Humanized mouse models are essential for investigating human gene function; however, the complete replacement of mouse genes ...

Cars patched up after a wreck may look fixed—but never run quite as before. The same may hold true for chromatin, according to a study published in Science on November 6. In response to double-strand ...

Explore RNA interference methods, comparing siRNA and shRNA for gene knockdown, their mechanisms, advantages, and ...

One person’s junk is another’s treasure. An international team of scientists have found that strings of “junk” DNA in the human genome that were previously written off as having no useful function are ...