Immunoglobulin G oligoclonal bands in CSF are highly prevalent in MS and CIS, with positive status associated with a significantly earlier age of disease onset.

Katharina Stoeck; Pascual Sanchez-Juan; Joanna Gawinecka; Alison Green; Anna Ladogana; Maurizio Pocchiari; Raquel Sanchez-Valle; Eva Mitrova; Theodor Sklaviadis ...

In this study, researchers aimed to determine whether ctDNA is detectable in other bodily fluids besides blood, and to characterize any ctDNA they were able to detect.

Study findings suggest that the unique genomic variations of cerebrospinal fluid can be leveraged as a liquid biopsy to effectively and safely improve decision-making regarding treatment of patients ...